JuveXO® SkinRevolutionizing skincare with the power of exosomes

Rejuvenate naturally with JuveXO®, designed to give skin a smoother, more luminous appearance, improve tone and texture, and reduce the visible signs of aging.

For professional use only.
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JuveXO® is a high-quality MSC-derived secretome produced through patent-pending technology. It provides the resources and nutrients necessary to give skin a natural, youthful-looking appearance.

JuveXO® has been specially engineered to contain high amounts of naturally occurring Types I and III Collagen, Elastin, Chondroitin Sulfate, Growth Factors, and High Molecular Weight Hyaluronic Acid— making JuveXO® ideal for cosmetic use.

Our serum is cell-free and produced from vigorously tested, postnatal human umbilical cord lining stem cells (ULSCs).

Over 100 billion exosomes per vial!

Intended use and benefits

JuveXO® Skin has a wide variety of benefits in supporting your skin to rejuvenate naturally

May improve appearance and enhance results following aesthetic procedures

May improve the appearance of sunspots, acne scarring, and other skin imperfections

May reduce wrinkles, fine lines, and other age-related imperfections

May enhance skin tone and texture

May improve the contour and shape of your face

May make skin look more hydrated, bright, and radiant

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JuveXO® Skin

Patient received Morpheus8 microneedling radiofrequency treatment to address normal signs of aging. Post-treatment, her skin was red and inflamed. JuveXO® was then applied topically to treated areas. Patient not only experienced visibly enhanced results, but her downtime was reduced and she was confident to step outside hours after treatment. These images were taken before and hours after treatment.

JuveXO® Skin

Patient experienced fine lines, dull skin tone, and sagging skin due to normal signs of aging. After receiving one XO Lift (microneedling treatment with JuveXO® application), she happily reported tighter appearance of skin and reduced appearance of wrinkles. These images were taken before and 1 month after XO Lift.

JuveXO® Skin

Patient experienced visible skin imperfections from unresolved atopic dermatitis. After applying JuveXO® topically using gauze (under the direction of a medical practitioner), patient noticed significant improvement in appearance of skin. These images were taken before and one month after application.

What are exosomes?

Exosomes are nano-sized, bioactive messengers that cells use to communicate with each other.

Exosomes from stem cells maintain a healthy physiological environment by introducing much needed young and vibrant proteins to the extracellular matrix and neighboring cells.

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Learn more about JuveXO®

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Erase Years of Aging

With as little as 5% application, JuveXO® demonstrated a significant improvement in collagen and elastin concentrations in the skin of 25 and 53-year-old JuveXO® patients (2).

Without JuveXO®, skin cells did not secrete detectable amounts of collagen or elastin in our this vitro study.

The Science Behind JuveXO

Over ten years of research has gone into the creation and perfection of JuveXO®, setting the bar for personalized rejuvenation. After extensive study of numerous stem cell sources, the scientific team behind JuveXO® discovered the unmatched potential of Mesenchymal Stem Cells (MSCs). Further comparison of colony formation, telomere length, and telomerase activity unveiled the unrivaled potential of ULSCs when compared to fat- and bone-derived stem cells.

Our Publications

JuveXO – premium biocosmetics backed by superior science and proven results.

How JuveXO® is made

1. Proprietary Stem

JuveXO® Exosomes from Pure Umbilical Cord Lining Stem Cells.

2. Rigorous Testing

Produced from vigorously tested, postnatal human umbilical cord lining stem cells (ULSCs), our serum is cell-free.

3. Optimized For Excellence

Stem cells are cultured to optimize components of the extra cellular matrix: Collagen I & III, Elastin, Chondroitin Sulfate, and high molecular weight Hyaluronic Acid.²

4. Cell-Free Sterile Serum

JuveXO® (cell-free, sterile serum) proteins, bioactive enzymes, and growth factors

5. JuveXO® Skin

Complete, superior serum. Use with cosmetic procedures or as topical facial rejuvenation procedure.

FAQs

Exosomes have made a significant breakthrough in the medical field. From therapeutic treatments for various medical conditions to topical treatments for common skin concerns, there is no doubt that exosomes have incredible potential.

As the buzz around exosomes continues to grow, many still ask the question – what are exosomes?
Exosomes are tiny little packages that cells use to communicate with each other. Think of them as the cell’s messengers, delivering important information and molecules like proteins, lipids, and nucleic acids from one cell to another. These tiny vesicles play a crucial role in cell-to-cell communication and can influence various biological processes.

It’s important to note that while exosomes hold great promise, further research is still needed to fully understand their mechanisms and full potential.
Exosomes are fascinating and versatile messengers that have the potential to revolutionize regenerative medicine. Exciting times lie ahead as scientists continue unraveling the mysteries of these tiny cellular communicators.

With as little as 5% UCM of JuveXO®, skin cells from both a 25 and 53 year-old patient produced more collagen and elastin(2).

Without JuveXO®, skin cells did not secrete detectable amounts of collagen or elastin in our in vitro study.

Each vial of JuveXO® is created with safety and integrity in mind. JuveXO is triple-filtered, characterized, and free of pathogenic viruses. All tissue used in the product for the purification of exosomes has been collected with informed consent and tested according to cGMP standards. Our vials have passed rigorous Container Closure Integrity Testing (CCIT).

The cell line used for JuveXO® has been tested and is free of numerous pathogenic viruses. Contact us for more details on our safety standards, donor screening, and extensive testing.

Over ten years of research has gone into the creation and perfection of JuveXO®, setting the gold standard for personalized rejuvenation.

After extensive study of numerous stem cell sources, the scientific team behind JuveXO® discovered the unmatched potential of Mesenchymal Stem Cells (MSCs). Further comparison of colony formation, telomere length, and telomerase activity unveiled the unrivaled potential of Umbilical Lining Stem Cells (ULSCs) when compared to fat- and bone-derived stem cells.

This compelling discovery of ULSC's potential led to incredible heights in innovative development. The scientific team behind JuveXO® began using these cutting-edge cells to isolate exosomes and secretomes for various clinical indications, and along the way, this research evolved into biocosmetic research – hello, JuveXO®.

Read the publications

SOURCES: 1. Gonzalez, R., et. al. An Efficient Approach to Isolation and Characterization of Pre-and Postnatal Umbilical Cord Lining Stem Cells for Clinical Applications. Cell Transplantation. 2010;19(1): 1439–1449. doi:10.3727/096368910X514260.
2. JuveXO®. Exosomes from Pure Umbilical Cord Lining Stem Cells Effect on Skin Fibroblast. Juvexo.com. 2019. https://www.juvexo.com/research-studies/. Accessed May 2020.
3. Zgheib C, Junwang X, Liechty K. Targeting Inflammatory Cytokines and Extracellular Matrix Composition to Promote Wound Regeneration. Adv Wound Care. 2014;3(4):344-355. doi:10.1089/wound.2013.0456<